The Substance 2024 Wiki.  — the substance — out september 20th — from writer / director coralie fargeat is a gruesome, feminist body horror for the age of ozempic. She and margaret qualley duke it out in.

 — in the substance, demi moore plays an aerobics tv star who turns 50 and is promptly ousted from her gig in hollywood. After premiering at the 2024 cannes film festival, the substance is coming to movie theaters in the us, uk and other locations on september 20 (early screenings starting.